On one level it is about a one night stand,
"We will never meet again so shed you your skin and lets get started" makes this fairly clear. But on a deeper level it is about love not lust, about the connection we all seek to that one soulmate. It also expresses the love of a parent to their child. Ona further level it expresses the loss of a love one and it used a lot at funeral usually for same line as quoted before. As with all classics people interperate their own meaning on to the song, this is what give a song universal appeal and usually commercial success. Not in this case it was never No1 in any chart but is a cult classic.

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